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Best AI model for Scientific Research (2026)

Reading papers, designing experiments, interpreting results. Ranked from 346 live models on the OpenRouter catalog, weighted for reasoning quality, context window.

#ModelScoreIn / 1MOut / 1MContext
1 Qwen: Qwen3.6 Plusqwen/qwen3.6-plus 136 $0.33 $1.95 1,000,000 Try →
2 xAI: Grok 4.20x-ai/grok-4.20 136 $2.00 $6.00 2,000,000 Try →
3 OpenAI: GPT-5.4 Nanoopenai/gpt-5.4-nano 136 $0.20 $1.25 400,000 Try →
4 OpenAI: GPT-5.4 Miniopenai/gpt-5.4-mini 136 $0.75 $4.50 400,000 Try →
5 OpenAI: GPT-5.4openai/gpt-5.4 136 $2.50 $15.00 1,050,000 Try →
6 Google: Gemini 3.1 Flash Lite Previewgoogle/gemini-3.1-flash-lite-preview 136 $0.25 $1.50 1,048,576 Try →
7 Qwen: Qwen3.5-Flashqwen/qwen3.5-flash-02-23 136 $0.07 $0.26 1,000,000 Try →
8 Google: Gemini 3.1 Pro Preview Custom Toolsgoogle/gemini-3.1-pro-preview-customtools 136 $2.00 $12.00 1,048,576 Try →
9 OpenAI: GPT-5.3-Codexopenai/gpt-5.3-codex 136 $1.75 $14.00 400,000 Try →
10 Google: Gemini 3.1 Pro Previewgoogle/gemini-3.1-pro-preview 136 $2.00 $12.00 1,048,576 Try →
11 Qwen: Qwen3.5 Plus 2026-02-15qwen/qwen3.5-plus-02-15 136 $0.26 $1.56 1,000,000 Try →
12 Google: Gemini 3 Flash Previewgoogle/gemini-3-flash-preview 136 $0.50 $3.00 1,048,576 Try →
13 OpenAI: GPT-5.2openai/gpt-5.2 136 $1.75 $14.00 400,000 Try →
14 Amazon: Nova 2 Liteamazon/nova-2-lite-v1 136 $0.30 $2.50 1,000,000 Try →
15 xAI: Grok 4.1 Fastx-ai/grok-4.1-fast 136 $0.20 $0.50 2,000,000 Try →

How we ranked these

For Scientific Research, we weight models on reasoning quality, context window. Higher means better. Scores combine OpenRouter's model metadata (context length, modality support, tool calling, structured output, reasoning capability) with public pricing. See full methodology →

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